At the Aerosol Research & Engineering Laboratories (ARE Labs), a U.S. laboratory specializing in the study of aerosolized microorganisms, Pyure conducted an evaluation of the reduction of several pathogens, including viruses, bacteria and mold.
Pyure efficacy was evaluated on five biosecurity level one (BSL-1) microorganisms that are considered representative of a broader range of more pathogenic organisms.
For copies of reports testing Pyure devices on other surface bound pathogens, please contact Pyure.
A study was designed and conducted by Innovative Bioanalysis LLC, a biosafety level 3 laboratory. The study demonstrated the efficacy of the Pyure device in reducing SARS-CoV-2, both in aerosolized form and on surfaces. Innovative Bioanalysis is certified laboratory located in Costa Mesa, Calif.
Comparative Biosciences, Inc. in compliance with the US Food & Drug Administration GLP regulations (21 CFR Part 58), conducted a 13-week toxicology study on the effects of elevated Pyure output levels on a statistically significant population of rats. Rat exposure levels were 2 to 3 times higher than the maximum levels recommended by Pyure. The results showed no adverse effects on treated animals vs. control animals after continuous exposure for 13 weeks, neither at the gross or cellular level.
This toxicology study, along with the mechanism of action and pathogen destruction studies, were submitted to the FDA as part of the 510k registration and listing for the Odorox® MDU/Rx™ unit. As part of the FDA submission, a review of NIH, CDC and other relevant government databases was conducted. The review did not reveal any data or evidence that natural natural or artificial hydroxyls are in any way toxic to humans, animals or plants.
These results were subsequently published in a peer reviewed scientific journal. (David R. Crosley, Connie J. Araps, Melanie Doyle-Eisele & Jacob D. McDonald (2017) Gas-phase photolytic production of hydroxyl radicals in an ultraviolet purifier for air and surfaces, Journal of the Air & Waste Management Association, 67:2, 231-240, DOI: 10.1080/10962247.2016.1229236).
The study examined the chemistry that resulted from hydroxyl decomposition of volatile organic compounds (VOC). The study revealed that operating a Pyure device significantly reduced total VOC levels, resulting in better indoor air quality. The VOC were rapidly decomposed and the steady state amounts of intermediate organic compounds, including formaldehyde, other aldehydes, ketones and alcohols did not accumulate while the Pyure device was running. The study detected very low levels of ozone (less than 15 parts per billion), far below the 50 part-per-billion maximum established by the FDA for continuous exposure. The study confirmed that Pyure Technology improves indoor air quality.
Pyure Technology uses UV energy to produce hydroxyls from water vapour, a process that also produces trace quantities of ozone as a byproduct. The sanitization power of Pyure Technology is driven by hydroxyls, not ozone. Hydroxyls are a million times more reactive than ozone.
It takes only a few parts per billion of hydroxyls to rapidly sanitize a space. Pyure devices produce hydroxyls at the same rate as nature.
Organic oxidants are formed when hydroxyls react with ambient volatile organic compounds (VOC) and oxygen. Organic oxidants are more stable than hydroxyls, allowing them to circulate through a treated space and clean, like they do in nature.
The quantity of ozone produced by Pyure’s most powerful portable device (The Odorox® Boss™ model) is 0.041g per hour.